TY  -  JOUR
AU  -  Tao, Hongbo
AU  -  Zhou, Xuan
AU  -  Liu, Yanqin
AU  -  Wang, Zhenlan
AU  -  Liu, Yunqin
AU  -  Su, Zou
AU  -  Ji, Qiuming
AU  -  Yi, Xianyun
AU  -  Wu, Xianghong
AU  -  Zhou, Qing
T1  -  Clinical effect of modified electroconvulsive therapy on schizophrenia
PY  -  2023
Y1  -  2023-07-01
DO  -  10.1708/4064.40481
JO  -  Rivista di Psichiatria
JA  -  Riv Psichiatr
VL  -  58
IS  -  4
SP  -  183
EP  -  189
PB  -  Il Pensiero Scientifico Editore
SN  -  2038-2502
Y2  -  2026/04/29
UR  -  http://dx.doi.org/10.1708/4064.40481
N2  -  Summary. Objective. To investigate the clinical efficacy of modified electroconvulsive therapy (MECT) in patients with schizophrenia and provide a reference for the selection of safe and effective treatment options in clinical practice. Methods. A total of 200 patients with schizophrenia, who were admitted to Wuhan Wudong Hospital Psychiatric Hospital from January 2019 to December 2020, were selected as the study subjects. They were divided into an observation group and a control group (100 cases in each group) according to a random number table. The control group was treated with conventional antipsychotics (risperidone and aripiprazole), and the observation group was given conventional antipsychotics (risperidone and aripiprazole) with MECT. After 8 weeks, the clinical efficacy, cognitive and memory functions and the occurrence of adverse reactions between the two groups were compared. Results. The total clinical effective rate of the observation group was 90%, which was higher than that of the control group (74%), and the difference was statistically significant (p<0.05). The Wisconsin Card Sorting Test results of the observation group were better than those of the control group, and the cognitive function of the observation group was better than that of the control group (p<0.05). The Wechsler Adult Intelligence Scale-Fourth Edition index of the observation group was higher than that of the control group, and the memory function of the observation group was better than that of the control group (p<0.05). The overall incidence of adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant (p=0.001). Conclusion. The application of MECT in patients with schizophrenia can produce a good clinical curative effect, which is beneficial to the improvement and promotion of memory and cognitive functions in patients. Since the occurrence of adverse reactions is controllable, and safety is ideal, MECT has value in clinical application.
ER  -