Settembre-Ottobre 2016, Vol. 51, N. 5 Riv Psichiatr 2016;51(5):206-211 | doi 10.1708/2476.25892 Scarica il PDF (77,7 kb) Validation of the Gambling Disorder Screening Questionnaire, a self-administered diagnostic questionnaire for gambling disorder based on the DSM-5 criteria titolo - split_articolo,controlla_titolo - art_titolo Validation of the Gambling Disorder Screening Questionnaire, a self-administered diagnostic questionnaire for gambling disorder based on the DSM-5 criteria title - controlla_titolo - art_title Validazione del Gambling Disorder Screening Questionnaire, un questionario diagnostico autosomministrato per il gioco d’azzardo patologico basato sui criteri del DSM-5 autori - vau_aut_id CORRADO VILLELLA1,2, MARCO PASCUCCI3, CHIARA DE WAURE4, ANTONELLO BELLOMO3, GIANLUIGI CONTE1 testo - art_testo E-mail: email@example.com affiliazione_autori - art_affiliazioni 1Istituto di Psichiatria, Università Cattolica del Sacro Cuore, Roma 2Dipartimento di Salute Mentale, Azienda Sanitaria Locale della Provincia di Foggia, Foggia 3Istituto di Psichiatria, Dipartimento di Medicina Clinica e Sperimentale, Università di Foggia 4Istituto di Igiene, Università Cattolica del Sacro Cuore, Roma riassunto - art_riassunto SUMMARY. Aims. The DSM-5 has modified the diagnostic criteria for gambling disorder, compared to the fourth edition of the manual; new diagnostic instruments are therefore needed. This study evaluated the psychometric characteristics of the Gambling Disorder Screening Questionnaire (GDSQ), a self-report questionnaire based on the DSM-IV and DSM-5 criteria for Gambling Disorder, measuring its validity, internal consistency, and submitting the questionnaire to a principal components analysis. Method. 71 patients from a gambling disorder outpatient clinic and 70 controls were evaluated with the GDSQ, the South Oaks Gambling Screen (SOGS), and a psychiatric interview. Results. The test showed a good sensibility, specificity, internal consistency, concurrent validity with the SOGS. The exclusion of the “illegal acts” item, and the lowering of the cut-off score to four positive items, as suggested by the DSM-5 criteria, improved the test sensibility and internal consistency. Discussion and conclusions. The GDSQ can be considered a useful screening test for Gambling Disorder. Furthermore, this study confirms the improved diagnostic accuracy of the criteria listed in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, compared to the previous edition. parolechiave - lingua - vke_key_id KEY WORDS: diagnostic criteria, Diagnostic and Statistical Manual of Mental Disorders, gambling disorder, diagnostic questionnaires, screening tests. abstract - art_abstract RIASSUNTO. Scopo. Il DSM-5 presenta delle modifiche nei criteri diagnostici per il gioco d’azzardo patologico, rispetto alla precedente edizione del manuale; è pertanto necessario sviluppare nuovi strumenti diagnostici. Questo studio ha valutato le caratteristiche psicometriche del Gambling Disorder Screening Questionnaire (GDSQ), un questionario sviluppato per l’autosomministrazione, basato sui criteri diagnostici del DSM-IV e del DSM-5 per il gioco d’azzardo patologico, misurandone la validità e la consistenza interna e sottoponendo il questionario all’analisi delle componenti principali. Metodi. 71 pazienti reclutati da un ambulatorio dedicato al gioco d’azzardo patologico e 70 controlli sono stati valutati con il GDSQ, con il South Oaks Gambling Screen (SOGS) e con valutazione psichiatrica. Risultati. Il test ha mostrato una buona sensibilità, specificità, consistenza interna, correlazione con il SOGS. L’esclusione del criterio degli atti illeciti e l’abbassamento del punteggio di cut-off a quattro criteri positivi, come suggerito dal DSM-5, migliora la sensibilità e consistenza interna del test. Discussione e conclusioni. Il GDSQ può essere considerato un utile test di screening per il gioco d’azzardo patologico. Inoltre, questo studio conferma il miglioramento nell’accuratezza diagnostica dei criteri elencati nella quinta edizione del Manuale Diagnostico e Statistico dei Disturbi Mentali rispetto alla precedente edizione. keyword - lingua - vke_key_id PAROLE CHIAVE: criteri diagnostici, Manuale Diagnostico e Statistico dei Disturbi Mentali, gioco d’azzardo patologico, questionari diagnostici, test di screening. testo - art_testo INTRODUCTION Gambling Disorder has been defined by the fifth edition of the Diagnostic and Statistical Manual of Mental Disorder (DSM-5)1 in the diagnostic criterion A as a persistent and recurrent problematic gambling behaviour leading to clinically significant impairment or distress, as indicated by the individual exhibiting four (or more) of the following, in a 12 month period: 1. needs to gamble with increasing amounts of money in order to achieve the desired excitement; 2. is restless or irritable when attempting to cut down or stop gambling; 3. has made repeated unsuccessful efforts to control, cut back or stop gambling; 4. is often preoccupied with gambling (e.g. having persistent thoughts of reliving past gambling experiences, handicapping or planning the next venture, thinking of ways to get money with which to gamble); 5. often gambles when feeling distressed (e.g. helpless, guilty, anxious, depressed); 6. after losing money gambling, often returns another day to get even (“chasing” one’s losses); 7. lies to conceal the extent of involvement with gambling; 8. has jeopardized or lost a significant relationship, job, or educational or career opportunity because of gambling; 9. relies on others to provide money to relieve desperate financial situations caused by gambling. Criterion B clarifies that the gambling behaviour must not be better explained by a manic episode. The fourth edition of the manual (DSM-IV)2 required five out of ten items to identify pathological gambling, considering the nine listed above plus one more, then listed as item 8: “has committed illegal acts such as forgery, fraud, theft, or embezzlement to finance gambling”. Reilly and Smith3 offer an overview on how the diagnostic criteria have been re-defined in the DSM-5. In recent years, a growing literature has aimed to estimate the prevalence of Pathological Gambling across different settings and populations. The most widely used diagnostic instrument has so far been the South Oaks Gambling Screen (SOGS)4, a 20-item self-report questionnaire developed to identify probable pathological gamblers, defined according to DSM-III5 criteria for pathological gambling. The SOGS has been widely used as a diagnostic instrument in epidemiological research, even if the diagnostic criteria for pathological gambling were modified in the fourth2 and in the fifth edition of the DSM1. A growing literature suggests that the SOGS tends to over-estimate the prevalence of this condition; Ladouceur et al.6 suggested that respondents might misunderstand or misinterpret the SOGS items. Epidemiological studies conducted with other instruments, based on DSM-IV criteria for pathological gambling, estimated a lower prevalence for this condition compared to SOGS-based surveys7,8. A number of questionnaires and interviews based on the DSM-IV criteria for pathological gambling have been developed in recent years9-15. The National Opinion Research Center DSM-IV Screen for Gambling Problems13,16, the Gambling Behavior Interview12, the Diagnostic Interview for Gambling Severity9 and Structured Clinical Interview for Pathological Gambling11 are structured interviews requiring a trained individual guiding the process. Unfortunately, data collected with different instruments and in different settings are not always comparable17,18. Following a paradigm already used by Stinchfield et al.12 in the Gambling Behavior Interview, we developed the Gambling Disorder Screening Questionnaire (GDSQ), a self-report questionnaire based on the DSM-IV criteria for pathological gambling, made of ten questions obtained paraphrasing the ten points of the criterion A of the DSM-IV2. We started from the diagnostic criteria listed in the DSM-IV because they included all the DSM-5 criteria; this procedure was used in order to check the effect of the exclusion of item 8 on the diagnostic accuracy of the test. Each question has two response options, affirmative or negative. Criterion B, the differential diagnosis of gambling as a symptom of a manic episode, was not included in the test. Our aim was to assess the psychometric characteristics of such instrument, measuring its validity, internal consistency, and to submit the questionnaire to a principal components analysis. Such analysis would help us to draw some considerations on the validity of the underlying diagnostic criteria for pathological gambling. METHODS Participants Patients Seventy-one patients consecutively acceding to our outpatient facility for gambling disorder were enrolled. 58 patients were male, 13 female. Their mean age was 47.56 years old, with a standard deviation of 14.07. All patients underwent a psychiatric evaluation, confirming the diagnosis of gambling disorder, and were administered the Modified International Neuropsychiatric Interview and the Addiction Severity Index, modified for Gambling Disorder. Controls Seventy participants, 56 males and 14 females, were recruited from a general practitioner’s ambulatory in the same urban area. The mean age was 46.64, with a standard deviation of 14.57. Materials Gambling Disorder Self-Report Screening Questionnaire The test is made of ten questions obtained paraphrasing the ten items of the DSM-IV Criterion A for Pathological Gambling. This is a self-report questionnaire; respondents are required to give dichotomous answers, yes or no, to each question. The sum of all affirmative answers gives the total score. The questionnaire is reported in the Box. South Oaks Gambling Screen4 The SOGS is a 20-items self-report questionnaire; designed to evaluate the presence of a pathological gambling behaviour. The first two items are scored on a Likert scale and converted to a binary scale; the next seventeen items are scored as binary answers, while the last is scored as “yes, current”, “yes, in the past”, or “no”. The first, second and twentieth answer are converted on a binary scale, then all the responses are summed in a total score. All affirmative answers are summed up to calculate the total score; a cut-off score of 5 is used to identify probable pathological gamblers. A cut off score of 2 identifies other, less problematic, at risk gamblers. Procedure Self-report questionnaires were administered with paper and pencil in an outpatient clinic for gambling disorder and in a general practitioner’s ambulatory in the same urban area. All the participants underwent a clinical evaluation in our outpatient clinic for gambling disorder, including a psychiatric interview aimed to confirm or exclude the diagnosis of gambling disorder. All participants signed an informed written consent before taking part to the study, which was approved by the ethical committee of our institution. Data analysis We have first measured the frequency of positive answers to each item. Afterward, the internal consistency of the 10 items questionnaire was assessed through the Cronbach’s Alpha for the whole scale and for each of the scales obtained eliminating one item at time from the test. Lastly, we conducted a principal component analysis, selecting the items proving the most accurate psychometric characteristics. We calculated the sensibility, specificity of the test –using the clinical evaluation as reference standard and the SOGS as comparator- both in 10 items version, with a cut-off score of five positive answers, and in the 9 items versions, with a cut-off of four positive answers, in order to compare the definitions from the last two editions of the DSM. The analyses were lead with the Stata 12 software. Concurrent validity was calculated with a linear regression analysis between the test scores and the scores from the South Oaks Gambling Screen. RESULTS Table 1 shows the mean value and the standard deviation for each item, while the mean value for the whole scale is 3.43, with a standard deviation of 3.55. Table 2 shows in the first column the correlation coefficient between each of the ten DSM-IV-TR items and the total scale score, while in the second column shows the value of the Cronbach’s Alpha of the scale obtained excluding each of the item. Table 3 shows the initial and extracted commonality value for each item, while the table 4 shoes the eigenvalue of each component, with the percentage of the variance explained and the cumulated percentage. Table 5 presents the matrix of components, with the correlation between each item and the first component. The principal component analysis displayed just one component explaining 58.9% of the variance of the totality of the items. Only this component showed an eigenvalue >1, with a value of 5.890. The second component has a value of only 0.984. The test showed a Sensibility of 98,6% and a specificity of 100%, while the version including all the DSM-IV criteria, requiring five positive items out of ten, showed a sensibility of 93,0% and a specificity of 100%. The SOGS offered a 100% sensibility and a 97.1% specificity. Both versions of the test show a good concurrent validity with the SOGS: the nine items version has a correlation coefficient of 0.47, p<0.001, 95% confidence interval between 0.44 and 0.50; the 10 items version has a coefficient of 0.49, p<0.001, 95% confidence interval between 0.46 and 0.52. DISCUSSIONS AND CONCLUSIONS This self report questionnaire can be considered as a useful screening diagnostic test for gambling disorder, with a good sensibility, specificity and internal consistency. Compared to the South Oaks Gambling Screen, the GDSQ offers a lower sensibility, but a higher specificity. Our test has the peculiarity of beeing derived from the current diagnostic definition and can be considered useful for screening purposes, as confirmed by the concurrent validity with the SOGS. The highest mean value was obtained by Item 6, while the lowest one by the item listed as the 8th in the DSM-IV (“illegal acts”); the “illegal acts” item had the lowest correlation coefficient with the scale, and the exclusion of this item improved the Cronbach’s alpha of the residual scale. Again, Item 8 had the lowest correlation with the first component, which could be called “Gambling Disorder”. Item 8 showed the lowest commonality value, and Item 6 the highest. The matrix of components displays the highest value for Item 6, the lowest for Item 8. Excluding Item 8 and lowering the cut-off score from five to four positive items increased the test sensibility in this sample, without reducing its specificity. These data confirm the improved diagnostic accuracy of the DSM 5 criteria, compared to those listed in the previous edition of the manual, and are in line with previous research by Denis and coworkers19 and by Petry and coworkers20,21, supporting the exclusion of the “illegal acts” criterion, and the lowering of the cut-off score, from five to four positive items. The principal component analysis displayed that the scale is unidimensional, suggestiong that all the items are expression of the same factor. Our study has one main limitation due to the small number of participants: the 100% sensibility for the SOGS is not in line with previous studies4,22 and the 100% specificity for the GDSQ will probably not be replicated by studies involving larger samples from general population. We must consider that our cases were recruited from an outpatient clinic focused on the treatment of gambling disorder, so a sampling bias could have influenced the results. All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 201323. Informed consent was obtained from all patients for being included in the study. Conflict of interest: the authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. Compliance with ethical standards: all procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments (World Medical Association 2013). biblio_titolo - ignora references bibliografia - art_bibliografia 1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fifth Edition DSM-5. Washington, DC: American Psychiatric Publishing, 2013. 2. 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